In this final video in our LABScon Replay series from LABScon 25, we present the keynote from SentinelLABS’ own Juan Andrés Guerrero-Saade (JAGS), VP, Intelligence & Security Research and Senior Technical Fellow.

In this engaging talk, Juan argues that cybersecurity is reaching the end of its experimental era. Years of piling complexity onto non-standardized software stacks have produced systems that are difficult to steer and costly to manage through human attention alone.

A key theme in the talk is JAGS’ argument that large language models change that equation. He describes them as a new source of cheap, effectively unlimited evaluative power and as a “lossy compression of human knowledge”. Used well, that kind of mechanized intelligence can give defenders a scalable way to assess, prioritize, and act without leaning so heavily on scarce human expertise. In practical terms, it lowers the cost of analysis and changes how defensive work can be done at scale.

That argument also shapes JAGS’ broader point about how security should evolve once this capability is built in rather than bolted on. Drawing on ideas from cybernetics, JAGS urges the industry to move beyond purely adversarial ‘agonistic’ design and toward systems in which human expertise and artificial evaluative power work together to produce better outcomes.

Rather than defending old product categories or familiar workflows, the talk points toward a more standardized, more automated, and more sustainable future for the industry. For anyone interested in how AI may reshape the practice, cost, and structure of cybersecurity itself, this keynote is essential viewing.

About the Author

Juan Andrés Guerrero-Saade (JAGS) is VP for Intelligence and Security Research and Senior Technical Fellow for AI Innovation, overseeing intelligence production and AI applications towards security problems. He’s also Distinguished Resident Fellow for Threat Intelligence at the Johns Hopkins SAIS Alperovitch Institute. His research work is the subject of two permanent exhibits at the International Spy Museum in Washington, DC. He’s a member of OpenAI’s Frontier Risk Council, founded the premier threat intelligence conference LABScon, and is a co-host of the Three Buddy Problem podcast.

LABScon 2026 | Call For Papers

Submission Deadline: June 19, 2026

LABScon is a unique venue for original research to be shared among peers. The benefit of an invite-only audience of researchers is that there’s no need for long preambles or introductions – speakers are encouraged to dive right into their technical findings.

• Original content only.
• Talks are 20 minutes long + 5 minutes for Q&A.
• Workshops are 90 minutes long.
• LABScon is primarily a threat intelligence and vulnerability research conference but we keep an open-mind.

About LABScon

This presentation was featured live at LABScon 2025, an immersive 3-day conference bringing together the world’s top cybersecurity minds, hosted by SentinelOne’s research arm, SentinelLABS.

Keep up with all the latest on LABScon here.